Tools for Glycan Analysis
 
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Many protein pharmaceuticals being developed for human use
are glycoproteins, with oligosaccharides covalently attached to the polypeptide side chains. The proportion of a glycoprotein which is oligosaccharide varies. Increasing evidence suggests that oligosaccharides can play  an important role in glyco-protein function. In evaluating the therapeutic effect and safety of a glycoprotein pharmaceutical, the intrinsic properties of the oligosaccharides as well as  their modulating effect on the protein must be considered and controlled.

novatec analytical is dedicated to supply the biopharma com- munity with the tools required for the analysis of recombinant biotherapeutics.

Our product line consists of:
 

Labeling Kits (sufficient reagents for up to 12-36 samples)
LudgerTag 2-AB Labeling Kit LT-KAB-A2
LudgerTag 2-AA Labeling Kit LT-KAA-A2
LudgerTag AA-AC Labeling Kit LT-KAAC-A2
LudgerTag 2-AP Labeling Kit LT-KAP-A2
 
CleanUp Cartridges (each 6 Cartridges)
LudgerClean E10 Cartridges LC-E10-A6 
LudgerClean S Cartridges LC-S-A6 
 
Carbohydrate HPLC Columns  
LudgerSep N HPLC Column LS-N1-4.6x250
LudgerSep C HPLC Column LC-C1-4.6x100
LudgerSep R HPLC Column LC-R1-4.6x150
Hydrazine  
Anhydrous Hydrazine (10 x 500 µl ampules) LK-HYDRAZINE-A10
Enzyme-Kits  
Carbohydrate N-Sequencing Kit KE-SQ01
Enzymatic CarboRelease Kit KE-DG01
Enzymes  
Endoglycosidases
PNGaseF, 300 mU, 60 µl E-PNG01
PNGaseF, 1U, 200 µl E-PNG05
PNGaseF, High Concentration, 1 U, 40 µl E-PNG09
Endo F1,1 U, 60 µl E-EF01
Endo F2, 1 U, 60 µl E-EF02
Endo F3, 330 mU, 60 µl E-EF03
Endo H, 300 mU, 60 µl E-EH02
O-Glycosidase, 75 mU, 60 µl E-G001
Exoglycosidases
Sialidase AU, a-(2-3,6,8,9), 300 mU, 60 µl E-S001
Sialidase CP, a-(2-3,6), 900 mU, 60 µl E-S005
Sialidase SP, a-(2-3),300 mU, 60 µl E-S007
α-(1-3,6)-Galactosidase, 24 U, 60 µl E-AG01
ß-(1-3,4,6)-Galactosidase, 360 mU, 60 µl E-BG01
ß-(1-3,4)-Galactosidase, 500 mU, 200 µl E-BG02
ß-(1-3,6)-Galactosidase, 3 U, 60 µl E-BG05
ß-(1-4)-Galactosidase, 180 mU, 60 µl E-BG07
Glucosaminidase, 2.4 U, 60 µl E-GL01
α-(1-2,3,6)-Mannosidase, 480 mU, 60 µl E-AM01
α-(1-6)-Mannosidase, 60 mU, 60 µl E-AM02
α-(1-3,4)-Fucosidase, 30 mU, 60 µl E-F002
α-(1-6)-Fucosidase, 30 mU, 60 µl E-F006
Carbohydrate Standards & Controls  
CarboLadder (Wheat starch ladder), 20 µg SA-L001
Fetuin, Control, 0.5 mg SA-F001
O-Linked Core 1 Glycan
Galactose-β (1-3)-GalNAc Glycan, 20 µg SA-CORE1
   
A4 Glycans
NA4 Glycan, 20 µg CN-NA4-20U
NGA4 Glycan, 20 µg CN-NGA4-20U
A3 Glycans
A3 Glycan, 20 µg CN-A3-20U
NA3 Glycan, 20 µg CN-NA3-20U
NGA3 Glycan, 20 µg CN-NGA3-20U
A2F Glycans
A2F Glycan CN-A2F-20U
A1F Glycan, 20 µg CN-A1F-20U
NA2F Glycan, 20 µg CN-NA2F-20U
NGA2F Glycan, 20 µg CN-NGA2F-20U
A2 Glycans
A2 Glycan, 20 µg CN-A2-20U
A1 Glycan, 20 µg CN-A1-20U
NA2 Glycan, 20 µg CN-NA2-20U
NGA2 Glycan, 20 µg CN-NGA2-20U
M3N2 Glycan, 20 µg CN-M3N2-20U
Miscellaneous Glycans
Hybrid Glycan, 20 µg CN-HYBRID-20U
Oligomannose Glycans
Man-9 Glycan, 20 µg CN-MAN9-20U
Man-8 Glycan, 20 µg CN-MAN8-20U
Man-7 Glycan, 20 µg CN-MAN7-20U
Man-6 Glycan, 20 µg CN-MAN6-20U
Man-5 Glycan, 20 µg CN-MAN5-20U
Analytical Services  
Please get in touch with us and inquire a  quotation for your specific application